Virginiamycin S1

Virginiamycin S1 is a streptozotocin B antibiotic produced by Streptomyces verticillioides, which has antibacterial activity by inhibiting bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation.

O=C1N2[C@](C(=O)N[C@H](C(=O)O[C@H](C)[C@H](NC(=O)C3=C(O)C=CC=N3)C(=O)N[C@H](CC)C(=O)N4[C@](C(=O)N(C)[C@H]1CC5=CC=CC=C5)(CCC4)[H])C6=CC=CC=C6)(CC(=O)CC2)[H]