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VDR agonist 1

Product Specifications

CAS Number

2269494-43-9

Target

Vitamin, Apoptosis, Others

Related Pathways

Apoptosis, Others, Metabolism

Bioactivity

VDR agonist 1 (compound 28), a nonsteroidal Vitamin D receptor (VDR) agonist, demonstrates potent activity with a low IC 50 of 690 nM in MCF-7 cells. It inhibits cell cycle progression through upregulation of p21 and p27, and induces apoptosis by elevating BAX expression while reducing Bcl-2 levels [1].

Smiles

C(CC)(CC)(C=1C=C(C(NCCN(CC)CC)=O)N(CC)C1)C2=CC(C)=C(/C=C/C(CC)(CC)O)C=C2

Molecular Formula

C32H51N3O2

Molecular Weight

509.77

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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