CaMKP inhibitor (sodium)
CaMKP inhibitor sodium (compound 5) is an inhibitor of Ca2+/neutral protein-dependent protein concentration (CaMKP) and its nuclear type (CaMKP-N) (IC50: 6.4 μM, CaMKP; 6.6 μM, CaMKP-N) . CaMKP is one type of Ser/Thr protein, which can be passed through to remove the oxidized oxidized protein (CaMK) . CaMKP inhibitor sodium inhibits CaMKP mediated phospho-CaMKI hydrolysis, unaffectes protein phosphoric acid 2C (PP2C) and calcineurin (CaN) [1].
Product Specifications
CAS Number
[52789-62-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
CaMK; Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/camkp-inhibitor-sodium.html
Purity
98.06
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=S(C1=C2C=CC=C(O)C2=C(N)C(S(=O)(O)=O)=C1)(O[Na])=O
Molecular Formula
C10H8NNaO7S2
Molecular Weight
341.30
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CAMK IV
Available Sizes
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