Urolithin B

Product Specifications

CAS Number

1139-83-9

Target

Endogenous Metabolite|||ERK|||AMPK|||JNK|||NF-?B|||Akt

Related Pathways

MAPK|||PI3K/Akt/mTOR signaling|||Chromatin/Epigenetic|||Metabolism|||Cytoskeletal Signaling|||NF-?B

Purity

0.9964

Bioactivity

Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical fruits, and medicinal herbs. Urolithin B inhibits NF-?B activity by reducing the phosphorylation and degradation of I?B?, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK. Urolithin B is also a regulator of skeletal muscle mass. Urolithin B has anti-inflammatory and antioxidant effects.