Urolithin B
Product Specifications
CAS Number
1139-83-9
Target
Endogenous Metabolite|||ERK|||AMPK|||JNK|||NF-?B|||Akt
Related Pathways
MAPK|||PI3K/Akt/mTOR signaling|||Chromatin/Epigenetic|||Metabolism|||Cytoskeletal Signaling|||NF-?B
Purity
0.9964
Bioactivity
Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical fruits, and medicinal herbs. Urolithin B inhibits NF-?B activity by reducing the phosphorylation and degradation of I?B?, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK. Urolithin B is also a regulator of skeletal muscle mass. Urolithin B has anti-inflammatory and antioxidant effects.
Smiles
Oc1ccc2c(c1)oc(=O)c1ccccc21
Molecular Formula
C13H8O3
Molecular Weight
212.2
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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