Umibecestat
Product Specifications
CAS Number
1387560-01-1
Target
Beta-Secretase, BACE
Related Pathways
Neuroscience
Purity
>99.99%
Bioactivity
Umibecestat is an inhibitor of beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1), with IC50s of 11 nM and 10 nM for human BACE-1 and mouse BACE-1, respectively. Umibecestat can be used for the research of alzheimer's disease.
Smiles
C[C@]1(CO[C@](C)(C(N)=N1)C(F)(F)F)c1nc(NC(=O)c2ncc(cc2Cl)C(F)(F)F)ccc1F
Molecular Formula
C19H15ClF7N5O2
Molecular Weight
513.8
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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