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Umibecestat

Product Specifications

CAS Number

1387560-01-1

Target

Beta-Secretase, BACE

Related Pathways

Neuroscience

Purity

>99.99%

Bioactivity

Umibecestat is an inhibitor of beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1), with IC50s of 11 nM and 10 nM for human BACE-1 and mouse BACE-1, respectively. Umibecestat can be used for the research of alzheimer's disease.

Smiles

C[C@]1(CO[C@](C)(C(N)=N1)C(F)(F)F)c1nc(NC(=O)c2ncc(cc2Cl)C(F)(F)F)ccc1F

Molecular Formula

C19H15ClF7N5O2

Molecular Weight

513.8

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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