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UK-370106

Product Specifications

CAS Number

230961-21-4

Target

MMP

Related Pathways

Proteases/Proteasome

Bioactivity

UK-370106 is a potent and highly selective inhibitor of MMP-3 (IC50: 23 nM) and MMP-12 (IC50: 42 nM), effectively inhibiting the cleavage of [3H]-fibronectin by MMP-3 (IC50: 320 nM) .

Smiles

CC1=C(C=CC(CCC[C@@H](C(N[C@H](C(N[C@H](COC)C2=CC=CC=C2)=O)C(C)(C)C)=O)CC(O)=O)=C1)C3=CC=CC=C3

Molecular Formula

C35H44N2O5

Molecular Weight

572.73

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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