PF-06733804
Product Specifications
CAS Number
1873373-33-1
Target
Trk receptor
Related Pathways
Tyrosine Kinase/Adaptors
Bioactivity
PF-06733804 is a potent inhibitor of pan-Trk in cell-based assays (IC50s: 8.4 nM, 6.2 nM, and 2.2 nM for TrkA, TrkB, and TrkC) with anti-hyperalgesic effect.
Smiles
O([C@H]1CN(C(CC2=CC=C(OC(F)(F)F)C=C2)=O)CC1(F)F)C=3C=C(C(NC)=O)C=NC3N
Molecular Formula
C20H19F5N4O4
Molecular Weight
474.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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