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Trilaciclib

Product Specifications

CAS Number

1374743-00-6

Target

Cell Cycle Arrest, CDK

Related Pathways

Cell Cycle/Checkpoint

Purity

0.99624

Bioactivity

Trilaciclib is a short-acting, orally effective CDK4/6 inhibitor with IC50 values of 1 nM and 4 nM respectively. It transiently and reversibly induces G1 cell cycle arrest, mitigates chemotherapy-induced myelosuppression, and enhances antitumour immunity, making it applicable across multiple cancers.

Smiles

CN1CCN(CC1)c1ccc(Nc2ncc3cc4C(=O)NCC5(CCCCC5)n4c3n2)nc1

Molecular Formula

C24H30N8O

Molecular Weight

446.55

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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