Trilaciclib
Product Specifications
CAS Number
1374743-00-6
Target
Cell Cycle Arrest|||CDK
Related Pathways
Cell Cycle/Checkpoint
Purity
0.9962
Bioactivity
Trilaciclib is a short-acting, orally effective CDK4/6 inhibitor with IC?? values of 1 nM and 4 nM respectively. It transiently and reversibly induces G1 cell cycle arrest, mitigates chemotherapy-induced myelosuppression, and enhances antitumour immunity, making it applicable across multiple cancers.
Smiles
CN1CCN(CC1)c1ccc(Nc2ncc3cc4C(=O)NCC5(CCCCC5)n4c3n2)nc1
Molecular Formula
C24H30N8O
Molecular Weight
446.55
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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