TPN171
Product Specifications
CAS Number
1229018-87-4
Target
PDE
Related Pathways
Metabolism
Purity
>99.99%
Bioactivity
TPN171 is potent PDE5 inhibitor with subnanomolar potency for PDE5 and good selectivity over PDE6, which has the potential for the treatment of pulmonary arterial hypertension (PAH) . TPN171 was proven to exert a longer lasting effect than sildenafil in animal models, providing a foundation for a once-daily oral administration for its clinical use.
Smiles
CCCOc1ccc(NC(=O)CN2CCN(C)CC2)cc1-c1nc(CC)c(CC)c(=O)[nH]1
Molecular Formula
C24H35N5O3
Molecular Weight
441.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
LV709102 1.0 µg DNA
CXorf57 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-C-term-HA)
Sign In for Pricing
View Details 
K7393607 1.0 µg DNA
Cpt1c sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2)
Sign In for Pricing
View Details GTR15175278 1 Vial
Lentiviral mouse Ptprf shRNA (UAS) - Lentiviral mouse Ptprf shRNA (UAS) (100)
Sign In for Pricing
View Details 