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TPN171

Product Specifications

CAS Number

1229018-87-4

Target

PDE

Related Pathways

Metabolism

Purity

>99.99%

Bioactivity

TPN171 is potent PDE5 inhibitor with subnanomolar potency for PDE5 and good selectivity over PDE6, which has the potential for the treatment of pulmonary arterial hypertension (PAH) . TPN171 was proven to exert a longer lasting effect than sildenafil in animal models, providing a foundation for a once-daily oral administration for its clinical use.

Smiles

CCCOc1ccc(NC(=O)CN2CCN(C)CC2)cc1-c1nc(CC)c(CC)c(=O)[nH]1

Molecular Formula

C24H35N5O3

Molecular Weight

441.57

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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