TPN171
Product Specifications
CAS Number
1229018-87-4
Target
PDE
Related Pathways
Metabolism
Purity
>99.99%
Bioactivity
TPN171 is potent PDE5 inhibitor with subnanomolar potency for PDE5 and good selectivity over PDE6, which has the potential for the treatment of pulmonary arterial hypertension (PAH) . TPN171 was proven to exert a longer lasting effect than sildenafil in animal models, providing a foundation for a once-daily oral administration for its clinical use.
Smiles
CCCOc1ccc(NC(=O)CN2CCN(C)CC2)cc1-c1nc(CC)c(CC)c(=O)[nH]1
Molecular Formula
C24H35N5O3
Molecular Weight
441.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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