Toceranib
Product Specifications
CAS Number
356068-94-5
Target
VEGFR, c-Kit, PDGFR
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
Purity
0.9762
Bioactivity
Toceranib (PHA 291639E) phosphate is an orally active inhibitor of tyrosine kinase (RTK) receptor, and it potently inhibits PDGFR, VEGFR, and Kit (with Kis of 5 and 6 nM for PDGFRβ and Flk-1/KDR, respectively), has antitumor and antiangiogenic activity.
Smiles
Cc1[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c(C)c1C(=O)NCCN1CCCC1
Molecular Formula
C22H25FN4O2
Molecular Weight
396.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS2045628-01 0.1 mL
APC/CY7-Linked Polyclonal Antibody to Glutathione S Transferase Mu 1 (GSTm1)
Sign In for Pricing
View Details MBS2045628-02 0.2 mL
APC/CY7-Linked Polyclonal Antibody to Glutathione S Transferase Mu 1 (GSTm1)
Sign In for Pricing
View Details MBS2045628-03 0.5 mL
APC/CY7-Linked Polyclonal Antibody to Glutathione S Transferase Mu 1 (GSTm1)
Sign In for Pricing
View Details MBS2045628-04 1 mL
APC/CY7-Linked Polyclonal Antibody to Glutathione S Transferase Mu 1 (GSTm1)
Sign In for Pricing
View Details MBS2045628-05 5 mL
APC/CY7-Linked Polyclonal Antibody to Glutathione S Transferase Mu 1 (GSTm1)
Sign In for Pricing
View Details MBS2045628-06 5x 5 mL
APC/CY7-Linked Polyclonal Antibody to Glutathione S Transferase Mu 1 (GSTm1)
Sign In for Pricing
View Details