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TG 100801 Hydrochloride

Product Specifications

CAS Number

1018069-81-2

Target

Src, FGFR, VEGFR, PDGFR

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis

Bioactivity

TG 100801 Hydrochloride is a prodrug to treat age-related macular degeneration. TG 100572 is a inhibitor of multi-targeted kinase (IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFRβ, Fgr, Fyn, Hck, Lck, Lyn, Src, Yes, respectively) .

Smiles

Cl.O=C(OC1=CC=C(Cl)C(=C1)C2=CC=3N=NC(=NC3C(=C2)C)NC4=CC=C(OCCN5CCCC5)C=C4)C=6C=CC=CC6

Molecular Formula

C33H31Cl2N5O3

Molecular Weight

616.54

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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