TG 100801 Hydrochloride
Product Specifications
CAS Number
1018069-81-2
Target
Src, FGFR, VEGFR, PDGFR
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
TG 100801 Hydrochloride is a prodrug to treat age-related macular degeneration. TG 100572 is a inhibitor of multi-targeted kinase (IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFRβ, Fgr, Fyn, Hck, Lck, Lyn, Src, Yes, respectively) .
Smiles
Cl.O=C(OC1=CC=C(Cl)C(=C1)C2=CC=3N=NC(=NC3C(=C2)C)NC4=CC=C(OCCN5CCCC5)C=C4)C=6C=CC=CC6
Molecular Formula
C33H31Cl2N5O3
Molecular Weight
616.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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