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TG 100572

Product Specifications

CAS Number

867334-05-2

Target

VEGFR|||FGFR|||PDGFR|||Src

Related Pathways

Angiogenesis|||Tyrosine Kinase/Adaptors

Bioactivity

TG 100572 is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases (IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 nM for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFR?, Fgr, Fyn, Hck, Lck, Lyn, Src, Yes, respectively) .

Smiles

ClC1=C(C2=CC3=C(C(C)=C2)N=C(NC4=CC=C(OCCN5CCCC5)C=C4)N=N3)C=C(O)C=C1

Molecular Formula

C26H26ClN5O2

Molecular Weight

475.97

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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