TG 100572
Product Specifications
CAS Number
867334-05-2
Target
VEGFR, FGFR, PDGFR, Src
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
Bioactivity
TG 100572 is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases (IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 nM for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFRβ, Fgr, Fyn, Hck, Lck, Lyn, Src, Yes, respectively) .
Smiles
ClC1=C(C2=CC3=C(C(C)=C2)N=C(NC4=CC=C(OCCN5CCCC5)C=C4)N=N3)C=C(O)C=C1
Molecular Formula
C26H26ClN5O2
Molecular Weight
475.97
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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