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TD-0212 TFA

Product Specifications

CAS Number

1073549-11-7

Target

RAAS, Neprilysin, Others

Related Pathways

Endocrinology/Hormones, Metabolism, Others

Bioactivity

TD-0212 TFA is an orally active dual pharmacology compound, functioning as an antagonist of the angiotensin II type 1 receptor (AT1) with a pKi of 8.9, and as an inhibitor of neprilysin (NEP) with a pIC50 of 9.2.

Smiles

OC(=O)C(F)(F)F.CCOc1nc(CC)c(CNC(=O)[C@@H](S)CC(C)C)n1Cc1ccc(cc1F)-c1ccccc1C(O)=O

Molecular Formula

C30H35F4N3O6S

Molecular Weight

641.67

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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