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CCR2 antagonist 4

Product Specifications

CAS Number

226226-39-7

Target

CCR

Related Pathways

GPCR/G Protein, Immunology/Inflammation, Microbiology/Virology

Purity

0.9986

Bioactivity

CCR2 antagonist 4 (Teijin compound 1) is a potent and specific CCR2 antagonist with IC50 values of 180 nM and 24 nM for CCR2 inhibition and MCP-1-induced chemotaxis inhibition, respectively.

Smiles

FC(F)(F)c1cccc(c1)C(=O)NCC(=O)N[C@@H]1CCN(Cc2ccc(Cl)cc2)C1

Molecular Formula

C21H21ClF3N3O2

Molecular Weight

439.86

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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