Pamufetinib
Product Specifications
CAS Number
1190836-34-0
Target
VEGFR, c-Met/HGFR
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
Purity
0.9939
Bioactivity
Pamufetinib (TAS-115) is a potent kinase inhibitor targeting VEGFR and the hepatocyte growth factor receptor (c-Met/HGFR), with IC50s of 30 nM for rVEGFR2 and 32 nM for rMET, respectively.
Smiles
O(C=1C2=C(C=C(OC)C(C(NC)=O)=C2)N=CC1)C3=C(F)C=C(NC(NC(CC4=CC=CC=C4)=O)=S)C=C3
Molecular Formula
C27H23FN4O4S
Molecular Weight
518.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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