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TCMDC-135051

Product Specifications

CAS Number

2413716-15-9

Target

Others|||Parasite

Related Pathways

Microbiology/Virology|||Others

Purity

0.9905

Bioactivity

TCMDC-135051 is a potent and selective PfCLK3 protein kinase inhibitor demonstrating significant antiparasiticidal activity (EC50=320 nM) while exhibiting minimal off-target toxicity. It effectively hinders the transition from trophozoite to schizont, impairs transcription, and diminishes transmission to the mosquito vector.

Smiles

CCN(CC)Cc1ccc(OC)c(c1)-c1cc2c(ccnc2[nH]1)-c1ccc(C(O)=O)c(c1)C(C)C

Molecular Formula

C29H33N3O3

Molecular Weight

471.59

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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