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TAS-114

Product Specifications

CAS Number

1198221-21-4

Target

Others, DNA/RNA Synthesis

Related Pathways

Others, DNA Damage/DNA Repair, Cell Cycle/Checkpoint

Purity

0.9976

Bioactivity

TAS-114 is an orally active dual inhibitor of dUTPase and dihydropyrimidine dehydrogenase (DPD) . TAS-114 targets the intercellular metabolism of 5-FU to enhance antitumor activity and modulates catabolic pathways to improve the systemic availability of 5-FU.

Smiles

C[C@@H](NS(=O)(=O)CCCOCn1ccc(=O)[nH]c1=O)c1cccc(OC2CCCC2)c1

Molecular Formula

C21H29N3O6S

Molecular Weight

451.54

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Frequently Asked Questions

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