TAS-114
Product Specifications
CAS Number
1198221-21-4
Target
Others, DNA/RNA Synthesis
Related Pathways
Others, DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Purity
0.9976
Bioactivity
TAS-114 is an orally active dual inhibitor of dUTPase and dihydropyrimidine dehydrogenase (DPD) . TAS-114 targets the intercellular metabolism of 5-FU to enhance antitumor activity and modulates catabolic pathways to improve the systemic availability of 5-FU.
Smiles
C[C@@H](NS(=O)(=O)CCCOCn1ccc(=O)[nH]c1=O)c1cccc(OC2CCCC2)c1
Molecular Formula
C21H29N3O6S
Molecular Weight
451.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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