TAK-828F
Product Specifications
CAS Number
1854901-94-2
Target
ROR
Related Pathways
Metabolism
Bioactivity
TAK-828F is a potent, selective, and orally available retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonist, with an IC50 of 1.9 nM and a reporter gene IC50 of 6.1 nM.
Smiles
C(NC=1C=C2C(=C(F)C1)C(C)(C)CC2)(=O)[C@H]3C=4C(CCN3C(=O)[C@H]5C[C@@H](CC(O)=O)C5)=NC(OC)=CC4
Molecular Formula
C28H32FN3O5
Molecular Weight
509.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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