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TAK-828F

Product Specifications

CAS Number

1854901-94-2

Target

ROR

Related Pathways

Metabolism

Bioactivity

TAK-828F is a potent, selective, and orally available retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonist, with an IC50 of 1.9 nM and a reporter gene IC50 of 6.1 nM.

Smiles

C(NC=1C=C2C(=C(F)C1)C(C)(C)CC2)(=O)[C@H]3C=4C(CCN3C(=O)[C@H]5C[C@@H](CC(O)=O)C5)=NC(OC)=CC4

Molecular Formula

C28H32FN3O5

Molecular Weight

509.57

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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