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T025

Product Specifications

CAS Number

2407433-00-3

Target

Apoptosis, DYRK, CDK

Related Pathways

Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint, Apoptosis

Purity

0.992

Bioactivity

T025 is a pan CLK inhibitor with Kds of 4.8, 0.096, 6.5, 0.61, and 0.074 nM for CLK1-4, respectively. T025 displays anti-proliferative activities with IC50s of 30-300 nM in hematological and solid cancer cell lines. T025 can be used in studies about MYC-driven diseases.

Smiles

CNc1nc(NCc2ncccn2)c2c(c[nH]c2n1)-c1ccc2ncccc2c1

Molecular Formula

C21H18N8

Molecular Weight

382.42

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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