T025
Product Specifications
CAS Number
2407433-00-3
Target
Apoptosis, DYRK, CDK
Related Pathways
Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint, Apoptosis
Purity
0.992
Bioactivity
T025 is a pan CLK inhibitor with Kds of 4.8, 0.096, 6.5, 0.61, and 0.074 nM for CLK1-4, respectively. T025 displays anti-proliferative activities with IC50s of 30-300 nM in hematological and solid cancer cell lines. T025 can be used in studies about MYC-driven diseases.
Smiles
CNc1nc(NCc2ncccn2)c2c(c[nH]c2n1)-c1ccc2ncccc2c1
Molecular Formula
C21H18N8
Molecular Weight
382.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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