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T-448

Product Specifications

CAS Number

1597426-53-3

Target

Histone Demethylase

Related Pathways

Chromatin/Epigenetic

Purity

0.9863

Bioactivity

T-448 is a specific, orally active, and irreversible inhibitor of lysine-specific demethylase 1 (LSD1, an H3K4 demethylase) with an IC50 of 22 nM.

Smiles

C(=C/C(O)=O)\C(O)=O.N([C@H]1[C@@H](C1)C2=CC(C(NC3=NN=C(C)S3)=O)=CC=C2)C4CCC4

Molecular Formula

C19H22N4O3S

Molecular Weight

386.47

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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