T-448

1597426-53-3

Histone Demethylase

Chromatin/Epigenetic

0.9863

T-448 is a specific, orally active, and irreversible inhibitor of lysine-specific demethylase 1 (LSD1, an H3K4 demethylase) with an IC50 of 22 nM.

C(=C/C(O)=O)\C(O)=O.N([C@H]1[C@@H](C1)C2=CC(C(NC3=NN=C(C)S3)=O)=CC=C2)C4CCC4

C19H22N4O3S

386.47

Ice Packs

-20°C