T-448
Product Specifications
CAS Number
1597426-53-3
Target
Histone Demethylase
Related Pathways
Chromatin/Epigenetic
Purity
0.9863
Bioactivity
T-448 is a specific, orally active, and irreversible inhibitor of lysine-specific demethylase 1 (LSD1, an H3K4 demethylase) with an IC50 of 22 nM.
Smiles
C(=C/C(O)=O)\C(O)=O.N([C@H]1[C@@H](C1)C2=CC(C(NC3=NN=C(C)S3)=O)=CC=C2)C4CCC4
Molecular Formula
C19H22N4O3S
Molecular Weight
386.47
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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