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Succinyl phosphonate

Product Specifications

CAS Number

26647-82-5

Target

Reactive Oxygen Species, ROS, Endogenous Metabolite

Related Pathways

Immunology/Inflammation, NF-κB, Metabolism

Bioactivity

Succinyl phosphonate is a selective α-ketoglutarate dehydrogenase (α-KGDHC) and OGDHC inhibitor that inhibits α-ketoglutarate oxidative decarboxylation. Succinyl phosphonate trisodium salt inhibits glutamate-induced ROS generation in glutamate-stimulated hippocampal neurons and can be used to study neurodegenerative diseases.

Smiles

O=C(O)CCC(=O)P(=O)(O)O

Molecular Formula

C4H7O6P

Molecular Weight

182.07

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Frequently Asked Questions

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