Succinyl phosphonate
Product Specifications
CAS Number
26647-82-5
Target
Reactive Oxygen Species, ROS, Endogenous Metabolite
Related Pathways
Immunology/Inflammation, NF-κB, Metabolism
Bioactivity
Succinyl phosphonate is a selective α-ketoglutarate dehydrogenase (α-KGDHC) and OGDHC inhibitor that inhibits α-ketoglutarate oxidative decarboxylation. Succinyl phosphonate trisodium salt inhibits glutamate-induced ROS generation in glutamate-stimulated hippocampal neurons and can be used to study neurodegenerative diseases.
Smiles
O=C(O)CCC(=O)P(=O)(O)O
Molecular Formula
C4H7O6P
Molecular Weight
182.07
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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