ADH-1 (trifluoroacetate)
Product Specifications
UNSPSC Description
ADH-1 trifluoroacetate is an N-cadherin antagonist, which inhibits N-cadherin mediated cell adhesion.
Target Antigen
Cadherin
Type
Peptides
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Exherin-trifluoroacetate.html
Smiles
O=C([C@@H](NC([C@H](C(C)C)NC([C@H](C)NC([C@H](CC1=CN=CN1)N2)=O)=O)=O)CSSC[C@H](NC(C)=O)C2=O)N.O=C(O)C(F)(F)F
Molecular Weight
684.71
References & Citations
[1]Shintani Y, et al. ADH-1 suppresses N-cadherin-dependent pancreatic cancer progression. Int J Cancer. 2008 Jan 1;122(1):71-7.|[2]Li H, et al. ADH1, an N-cadherin inhibitor, evaluated in preclinical models of angiogenesis and androgen-independent prostate cancer. Anticancer Drugs. 2007 Jun;18(5):563-8.|[3]Turley RS, et al. Targeting N-cadherin increases vascular permeability and differentially activates AKT in melanoma. Ann Surg. 2015 Feb;261(2):368-77
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-13541A/ADH-1-trifluoroacetate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-13541A/ADH-1-trifluoroacetate-SDS-MedChemExpress.pdf
CAS Number
1135237-88-5
Available Sizes
Curated Selection
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