11-Deoxyprostaglandin F2β

11-Deoxyprostaglandin F2β (11-deoxy PGF2β) is an analog of PGF2β (HY-12956B) . PGF2β is a metabolite produced by cyclooxygenase metabolism of arachidonic acid. PGF2β induces dose-dependent release of hexose containing mucin[1][2][3].

Product Specifications

CAS Number

[37786-07-5]

Product Name Alternative

11-Deoxy-PGF2β

UNSPSC

12352211

Hazard Statement

H225-H319-H336-H360

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/11-deoxyprostaglandin-f2β.html

Solubility

10 mM in DMSO

Smiles

OC(CCC/C=C\C[C@@H]1[C@H](CC[C@H]1O)/C=C/[C@@H](O)CCCCC)=O

Molecular Formula

C20H34O4

Molecular Weight

338.48

Precautions

P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P370+P378-P403+P233-P403+P235-P405-P501

References & Citations

[1]Mizsak SA, et al. Assignment of 9- and 11- configuration in prostaglandins by CMR. Prostaglandins. 1975 Nov;10 (5) :807-12.|[2]Jang Y, et al. Molecular mechanisms underlying the actions of arachidonic acid-derived prostaglandins on peripheral nociception. J Neuroinflammation. 2020 Jan 22;17 (1) :30.|[3]Lamont JT, et al. Cysteamine and prostaglandin F2 beta stimulate rat gastric mucin release. Gastroenterology. 1983 Feb;84 (2) :306-13.