SNDX-5613
Product Specifications
CAS Number
2169919-21-3
Target
Histone Methyltransferase, Epigenetic Reader Domain
Related Pathways
Chromatin/Epigenetic
Purity
0.9974
Bioactivity
Revumenib (SNDX-5613) is a potent and selective oral inhibitor of menin-KMT2A interaction with Ki of 0.149 nM and IC50 between 10 and 20 nM, which can be used in the study of acute leukemia with MLL gene rearrangement.
Smiles
CCN(C(C)C)C(=O)c1cc(F)ccc1Oc1cncnc1N1CC2(C1)CCN(C[C@H]1CC[C@@H](CC1)NS(=O)(=O)CC)CC2
Molecular Formula
C32H47FN6O4S
Molecular Weight
630.82
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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