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SNDX-5613

Product Specifications

CAS Number

2169919-21-3

Target

Histone Methyltransferase|||Epigenetic Reader Domain

Related Pathways

Chromatin/Epigenetic

Purity

0.9974

Bioactivity

Revumenib (SNDX-5613) is a potent and selective oral inhibitor of menin-KMT2A interaction with Ki of 0.149 nM and IC50 between 10 and 20 nM, which can be used in the study of acute leukemia with MLL gene rearrangement.

Smiles

CCN(C(C)C)C(=O)c1cc(F)ccc1Oc1cncnc1N1CC2(C1)CCN(C[C@H]1CC[C@@H](CC1)NS(=O)(=O)CC)CC2

Molecular Formula

C32H47FN6O4S

Molecular Weight

630.82

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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