Levosulpiride
Levosulpiride (RV-12309) is the (S) -enantiomer of sulpiride, which is a D2 receptor a antagonist, an atypical antipsychotic agent of the benzamide class.
Product Specifications
CAS Number
23672-07-3
Product Name Alternative
RV-12309; S- (-) -Sulpiride
UNSPSC
12352005
Target
5-HT Receptor; Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Levosulpiride.html
Purity
99.87
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(NC[C@H]1N(CC)CCC1)C2=CC(S(=O)(N)=O)=CC=C2OC
Molecular Formula
C15H23N3O4S
Molecular Weight
341.43
References & Citations
[1]Arif ST, et al., Enhanced Antidepressant Activity of Nanostructured Lipid Carriers Containing Levosulpiride in Behavioral Despair Tests in Mice. Pharmaceuticals (Basel) . 2023 Aug 29;16 (9) :1220.|[2]Akrab SNA, et al., The role of mosapride and levosulpiride in gut function and glycemic control in diabetic rats. Arab J Gastroenterol. 2023 May;24 (2) :109-116.|[3]Tonini M, et al., 5-HT4 receptors contribute to the motor stimulating effect of levosulpiride in the guinea-pig gastrointestinal tract. Dig Liver Dis. 2003 Apr;35 (4) :244-50.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
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