SM-164 Hydrochloride (957135-43-2 free base)
Product Specifications
Target
IAP
Related Pathways
Apoptosis
Bioactivity
SM-164 Hydrochloride is a cell-permeable Smac mimetic compound. SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50 value of 1.39 nM) and functions as an extremely potent antagonist of XIAP.
Smiles
C[C@H](NC)C(N[C@H]1CCCC[C@](CC[C@H]2C(N[C@@H](C3=CC=CC=C3)C4=CN(CCCCC5=CC=C(CCCCN6N=NC([C@@H](NC([C@@H]7CC[C@@](CCCC[C@@H]8NC([C@@H](NC)C)=O)([H])N7C8=O)=O)C9=CC=CC=C9)=C6)C=C5)N=N4)=O)([H])N2C1=O)=O.Cl
Molecular Formula
C62H85ClN14O6
Molecular Weight
1157.88
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
13435-01 200 mL
10X Phosphate Buffered Saline Tween-20 (PBST) for molecular biology
Ask
View Details 
13435-02 1000 mL
10X Phosphate Buffered Saline Tween-20 (PBST) for molecular biology
Ask
View Details 
227132-ML405 100 µL
PSA (Prostate-Specific antigen, Kallikrein 3, KLK3) (MaxLight 405) discontinued
Ask
View Details