SM-164 Hydrochloride (957135-43-2 free base)
Product Specifications
Target
IAP
Related Pathways
Apoptosis
Bioactivity
SM-164 Hydrochloride is a cell-permeable Smac mimetic compound. SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50 value of 1.39 nM) and functions as an extremely potent antagonist of XIAP.
Smiles
C[C@H](NC)C(N[C@H]1CCCC[C@](CC[C@H]2C(N[C@@H](C3=CC=CC=C3)C4=CN(CCCCC5=CC=C(CCCCN6N=NC([C@@H](NC([C@@H]7CC[C@@](CCCC[C@@H]8NC([C@@H](NC)C)=O)([H])N7C8=O)=O)C9=CC=CC=C9)=C6)C=C5)N=N4)=O)([H])N2C1=O)=O.Cl
Molecular Formula
C62H85ClN14O6
Molecular Weight
1157.88
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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