(Rac) -SIS3 free base
Product Specifications
CAS Number
1009104-85-1
Target
TGF-beta/Smad
Related Pathways
Stem Cells
Bioactivity
SIS3 free base is a potent and selective inhibitor of Smad3 phosphorylation, effectively inhibiting the TGF-?1-induced myofibroblast differentiation of fibroblasts.
Smiles
COc1cc2CCN(Cc2cc1OC)C(=O)\C=C\c1c(-c2ccccc2)n(C)c2ncccc12
Molecular Formula
C28H27N3O3
Molecular Weight
453.53
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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