(Rac) -SIS3 free base

Product Specifications

CAS Number

1009104-85-1

Target

TGF-beta/Smad

Related Pathways

Stem Cells

Bioactivity

SIS3 free base is a potent and selective inhibitor of Smad3 phosphorylation, effectively inhibiting the TGF-?1-induced myofibroblast differentiation of fibroblasts.

Smiles

COc1cc2CCN(Cc2cc1OC)C(=O)\C=C\c1c(-c2ccccc2)n(C)c2ncccc12

Molecular Formula

C28H27N3O3

Molecular Weight

453.53

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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