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SARS-CoV-2 (COVID-19) NSP8 Protein, His Tag

SARS-CoV-2 NSP8, His Tag (NS8-C5149) is expressed from E. coli cells. It contains AA Ala 1 - Gln 198 (Accession # YP_009725304.1) .

Product Specifications

Background

NSP8, forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers. To ultimately combat the emerging COVID-19 pandemic, it is desired to develop an effective and safe vaccine against this highly contagious disease caused by the SARS-CoV-2 coronavirus. By investigating the entire proteome of SARS-CoV-2, six proteins, including the S protein and five non-structural proteins (nsp3,3CL-pro, and nsp8-10) were predicted to be adhesins, which are crucial to the viral adhering and host invasion. The S, nsp3, and nsp8 proteins were also predicted by Vaxign-ML to induce high protective antigenicity.

Specifications

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 23.9 kDa. The protein migrates as 22-25 kDa under reducing (R) condition (SDS-PAGE) .

Accession Number

YP_009725304.1

Expression Region

Ala 1 - Gln 198

Host

E. coli

Target

NSP8

Conjugation

Unconjugated

Tag

N-10xHis

Source

SARS-CoV-2

Stability

● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.

Endotoxin

1.0 EU per μg

Purity

95%

Format

Liquid

Buffer

20 mM Tris, 250 mM NaCl, pH8.5

Additives

Glycerol

Molecular Weight

23.9 kDa

Shipping Conditions

Dry ice

Storage Conditions

-70°C

Package Size

1mg*1

Product Datasheet

Https://www.acrobiosystems.com/static/main/products/pdf/ds/NS8-C5149.pdf

Species

SARS-CoV-2

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