LY113174
LY113174 is an orally active aromatase inhibitor (IC50 = 24 nM) . LY113174 blocks testosterone induced increase in uterine weight in rat, and inhibits ovarian estrogen biosynthesis[1].
Product Specifications
CAS Number
112959-07-6
UNSPSC
12352005
Target
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/ly113174.html
Smiles
ClC1=CC=C(C=C1)C2C3=C(C=C(C=C3)Cl)C4=NC=NC=C42
Molecular Formula
C17H10Cl2N2
Molecular Weight
313.18
References & Citations
[1]Hirsch KS, et al. Discovery and development of a novel class of nonsteroidal aromatase inhibitors. Steroids. 1987 Jul-Sep;50 (1-3) :201-17.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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