Recombinant Human VEGF Protein (His Tag)
Product Specifications
Background
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF) /vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, inhibiting apoptosis and tumor growth. VEGF-A protein is also a vasodilator that increases microvascular permeability, thus it was originally referred to as vascular permeability factor.
Abbreviation
VEGF
Synonyms
MVCD; Vascular Endothelial Growth Factor Isoform; VEGFA; MVCD1; VEGF; VPF; L VEGFA; VEGF A; Folliculostellate cell-derived growth factor; Glioma-derived endothelial cell mitogen; Vascular Endothelial Growth Factor Isoform 165; Vascular permeability factor; VEGF121; VEGF165; VEGF-165; VEGF-A; Vascular endothelial growth factor A; Vascular permeability factor (VPF) ; MVCD1; vascular endothelial growth factor A; VEGF; VPF; MGC70609; vascular endothelial growth factor; vascular endothelial growth factor A121; vascular endothelial growth factor A165; VEGF120
UniProt
P15692
Accession Number
P15692
Expression System
Mammalian
Tag
C-His
Sequence
Met1-Arg165
Field of Research
Cancer; Cardiovascular; Developmental Biology; Signal Transduction
Endotoxin
< 1.0 EU/mg of the protein as determined by the LAL method
Purity
> 90% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
18 kDa
Observed Molecular Weight
18-24 kDa
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Species
Human
Available Sizes
Curated Selection
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