Biotin-PEG2-NHS ester

Biotin-PEG2-NHS ester is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[596820-83-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/biotin-peg2-nhs-ester.html

Purity

96.65

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(NCCOCCOCCC(ON1C(CCC1=O)=O)=O)CCCCC2SCC(C2N3)NC3=O

Molecular Formula

C21H32N4O8S

Molecular Weight

500.57

Precautions

H302, H315, H319, H335

References & Citations

[1]Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13 (5) :514-521.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Available Sizes

Curated Selection

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