(R) - (+) -Atenolol

(R) - (+) -Atenolol is the less active enantiomer of the (R, S) -atenolol. (R, S) -atenolol is a β-adrenergic receptor antagonist[1][2].

Product Specifications

CAS Number

[56715-13-0]

UNSPSC

12352005

Hazard Statement

H315, H319, H320

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Others; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/r-atenolol.html

Concentration

10mM

Purity

99.0

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(N)CC1=CC=C(OC[C@H](O)CNC(C)C)C=C1

Molecular Formula

C14H22N2O3

Molecular Weight

266.34

Precautions

H315, H319, H320

References & Citations

[1]Batra S, et al. Bioassay, determination and separation of enantiomers of atenolol by direct and indirect approaches using liquid chromatography: A review. Biomed Chromatogr. 2018 Jan;32 (1) .|[2]Stoschitzky K, et al. Stereoselective features of (R) - and (S) -atenolol: clinical pharmacological, pharmacokinetic, and radioligand binding studies. Chirality. 1993;5 (1) :15-9.