Fumagillin (Standard)
Fumagillin (Standard) is the analytical standard of Fumagillin. This product is intended for research and analytical applications. Fumagillin (NSC9168) is an antimicrobial compound first isolated in 1949 from the fungus Aspergillus fumigatu. Fumagillin can inhibits HIV‐1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity.
Product Specifications
CAS Number
23110-15-8
Product Name Alternative
Amebacilin (Standard) ; NSC9168 (Standard)
UNSPSC
12352005
Target
Antibiotic; HIV; Parasite; Reference Standards
Type
Reference Standards
Related Pathways
Anti-infection; Others
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/fumagillin-standard.html
Smiles
C[C@]1([C@@H](C/C=C(C)/C)O1)[C@]([C@@H]2OC)([H])[C@]3(CC[C@H]2OC(/C=C/C=C/C=C/C=C/C(O)=O)=O)CO3
Molecular Formula
C26H34O7
Molecular Weight
458.54
References & Citations
[1]Lefkove, B., B. Govindarajan, and J.L. Arbiser, Fumagillin: an anti-infective as a parent molecule for novel angiogenesis inhibitors. Expert Rev Anti Infect Ther, 2007. 5 (4) : p. 573-9.|[2]Watanabe N, et al. Fumagillin suppresses HIV-1 infection of macrophages through the inhibition of Vpr activity. FEBS Lett. 2006 May 15;580 (11) :2598-602.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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