Calycosin
Calycosin is a compound that can be isolated from Radix Astragali. Calycosin has strong antioxidant, anti-inflammatory and apoptosis-modulating effects. Calycosin can be used for the research of ovarian cancer and breast cancer[1][2].
Product Specifications
CAS Number
20575-57-9
Product Name Alternative
Cyclosin
UNSPSC
12352005
Hazard Statement
H301
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Calycosin.html
Purity
99.96
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C1C(C2=CC=C(OC)C(O)=C2)=COC3=CC(O)=CC=C13
Molecular Formula
C16H12O5
Molecular Weight
284.26
Precautions
H301
References & Citations
[1]Zhou Y, et al. Calycosin induces apoptosis in human ovarian cancer SKOV3 cells by activating caspases and Bcl-2 family proteins. Tumour Biol. 2015 Feb 12.|[2]Chen J, et al. Calycosin promotes proliferation of estrogen receptor-positive cells via estrogen receptors and ERK1/2 activation in vitro and in vivo. Cancer Lett. 2011 Sep 28;308 (2) :144-51.|[3]Guo C, et al. Neuroprotective effect of calycosin on cerebral ischemia and reperfusion injury in rats. J Ethnopharmacol. 2012 Dec 18;144 (3) :768-74.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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